We support the pioneering research of the late Nobel Laureate Dr. Paul Greengard under the leadership of Dr. Marc Flajolet and his team as they continue pursuing the quest for a cure. Add Impact to Your Inbox Thank you! Your submission has been received! Something went wrong while submitting the form. Thank you! We consistently receive top awards and ratings for our accountability:. Alzheimer's disease is an irreversible degeneration of the brain that causes disruptions in memory, cognition, personality, and other functions that eventually lead to death from complete brain failure.
More than 5. By , nearly 14 million Census suggest that this number may be as high as 16 million. Every 65 seconds, someone in America develops Alzheimer's. By mid-century, someone in America will develop the disease every 33 seconds. Worldwide, at least 50 million people are believed to be living with Alzheimer's disease or other dementias. In the time it takes to read this sentence out loud, another person somewhere in the world has been diagnosed with dementia.
According to public financial statements, that is more than the profits of Apple, J. P Morgan Chase and Berkshire Hathaway combined. More than 16 million Americans, usually family and friends, provide unpaid care for someone with Alzheimer's disease or dementias. In , these people provided an estimated Caring for a person with Alzheimer's or another dementia is often extremely difficult, and many family and other unpaid caregivers experience high levels of emotional stress and depression as a result.
Caring for someone with Alzheimer's disease has been found to have a negative impact on the health, employment, income, and financial security of many caregivers. For those 65 and older, it is the fifth-leading cause of death. Alzheimer's disease is currently underreported as the underlying cause of death—there is a difference between dying with Alzheimer's and death from Alzheimer's. A recent study found the Alzheimer's mortality rate to be five to six times higher than official estimates, suggesting that AD may be responsible for more than , annual deaths in the United States.
Source: Prince, M et al The global picture of dementia prevalence is complex and affected by a variety of different factors, from life expectancy to quality of health data reporting. Here you can see how these different factors interact based on regional and income boundaries.
The majority of people with dementia worldwide live in middle income countries and the number is projected to grow both absolutely and as a proportion of global prevalence. The change in the numbers of people with dementia is expected to increase far more rapidly in the upper middle, lower middle and low income countries than in the high income countries. Even in these high income countries, the number of people is expected to more than double.
Low income countries tend to have a lower life expectancy, which reduces the prevalence of dementia. In upper middle income countries, life expectancy and populations are increasing, leading to a greater number of people with dementia. High income countries have broadly already experienced the increases in health and population that these upper middle income countries are undergoing and so prevalence is high but will not rise as rapidly.
The geographic picture of global dementia prevalence is more complex due to the considerable differences between countries in the same global region which is why, in the graph below, there is less variation between the regions. The number of people with dementia is expected to rise more rapidly in Asia compared to the rest of the world due to the rapidly rising population.
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