Examining Soma vs. Tizanidine , the two drugs are quite similar. Both treat muscle spasms and are available in generic forms. Neither is considered a first-option medication, and both can be problematic when used by elderly patients.
As for what makes them different, Zanaflex does not last as long and takes longer for effects to kick in. Some consider Zanaflex stronger than Carisoprodol, and it also comes with significantly more side effects, many of them dangerous. People tend to rate Zanaflex lower in terms of effectiveness. Given that when comparing Soma vs. Comparing Valium vs. Soma can be difficult because the medications are from two different drug classes.
Valium is a benzodiazepine while Carisoprodol is a muscle relaxant. Technically, both will relax the muscles, but in the case of Valium, that is more a side effect than the purpose of the drug. Valium causes more actions on the body than Carisoprodol, and as a result, has more side effects.
As a result, it has a higher potential for addiction and abuse. However, many people consider it to be a more potent drug with longer-lasting results. Since it is also cheaper, it is considered by many to be an ideal alternative. Lorzone vs. Soma comparison is interesting as the two medications are seemingly very similar. They are both meant for short-term use, restricted in their application with elderly patients, and are considered secondary choices due to their significant side effects.
Ultimately, they are apart because Lorzone is significantly more expensive than Carisoprodol, and it is rated much lower by users. Tramadol and Soma are two very different drugs. Tramadol belongs to the drug class opiate analgesics and is specifically designed to treat pain by acting on the opioid receptors, unlike Carisoprodol, which treats pain by relaxing the muscles.
Both medications are effective at treating different types of pain and are considered addictive. However, tramadol has more significant side effects. It means that in the debate of tramadol vs. Carisoprodol, doctors should only select tramadol if it is clear it will treat the condition better than Carisoprodol.
Overall, they are of equal effectiveness but on different types of pain, with tramadol being the more affordable choice. Anyone who wants to stop Carisoprodol use should do so in a supervised setting. At a drug rehabilitation center , the right detox treatments and guidance are available.
Then once detoxed, other treatment options can be used. Soma alternatives can help fulfill the ultimate treatment goal. Roger Weiss is a practicing mental health specialist at the hospital. Weiss combines his clinical practice and medical writing career since Estimated cost to the pharmacist based on average wholesale prices rounded to the nearest dollar in Red Book. Montvale, N. Cost to the patient will be higher, depending on prescription filling fee.
Information from references 1 through 9. Among antispasmodic agents, carisoprodol Soma , cyclobenzaprine Flexeril , metaxalone Skelaxin , and methocarbamol Robaxin were among the top drugs dispensed in the United States in The American Pain Society and the American College of Physicians recommend using acetaminophen and nonsteroidal anti-inflammatory drugs NSAIDs as first-line agents for acute low back pain and reserving skeletal muscle relaxants as an alternative treatment option.
Similar recommendations exist in treating tension headaches. Prescription rates for nonspecific back pain revealed that skeletal muscle relaxants accounted for This article presents evidence regarding the use of antispasmodic skeletal muscle relaxants for various musculoskeletal conditions, and appropriate drug selection if a skeletal muscle relaxant is required. Highlights of contraindications, adverse effects, and drug interactions for these drugs are listed in Table 1.
Many of the studies evaluating the effectiveness of skeletal muscle relaxants are hampered by poor methodologic design, including incomplete reporting of compliance, improper or no mention of allocation concealment, not utilizing intention-to-treat methods, and inadequate randomization.
Some evidence appears to support nonbenzodiazepine skeletal muscle relaxants, such as carisoprodol, cyclobenzaprine, orphenadrine Norflex , and tizanidine Zanaflex , for acute low back pain. One fair-quality study showed no difference between metaxalone and placebo. Cyclobenzaprine has been the most heavily studied drug, with consistently proven effectiveness. Cyclobenzaprine was found to be moderately more effective than placebo, but had more central nervous system adverse effects.
The authors also described several limitations of the meta-analysis including inadequate blinding, heterogeneity among studies, and the presence of publication bias. Skeletal muscle relaxants have also been studied as adjunctive therapy to analgesics in treating acute low back pain. In one open-label study 20 patients , the addition of cyclobenzaprine to naproxen Naprosyn resulted in a statistically significant decrease in muscle spasm and tenderness compared with naproxen alone.
Cyclobenzaprine has also been studied in treating fibromyalgia. A meta-analysis of five trials ranging from six to 24 weeks' duration included a total of patients with fibromyalgia. The authors reported that, although cyclobenzaprine moderately improved sleep and pain, the long-term benefits were unknown. This meta-analysis was limited by a high drop-out rate, short trial duration, few studies having an intention-to-treat design, and inadequate blinding.
Strong data comparing skeletal muscle relaxants to each other are scarce. A systematic review evaluated 46 trials head-to-head and placebo-controlled comprising mostly of studies on low back pain or neck syndromes. The placebo-controlled trials included 17 on cyclobenzaprine, six on tizanidine, four on carisoprodol, and four on orphenadrine, and were mostly conducted more than 15 years ago. The average patient enrollment was less than patients range 12 to patients.
In general, all of the drugs were shown to have some benefit. One fair-quality study showed carisoprodol was better than diazepam at improving muscle spasm and global and functional status in patients with low back pain. A different systematic review did include some studies which were considered to be high quality. Although the evidence for effectiveness of skeletal muscle relaxants in musculoskeletal conditions is limited, strong evidence does exist in terms of toxicity.
Selection of a skeletal muscle relaxant should be individualized to the patient. If there are tender spots over the muscle or trigger points on physical examination, a skeletal muscle relaxant is a reasonable adjunct to analgesic treatment of low back pain. Skeletal muscle relaxants may also be used as an alternative to NSAIDs in patients who are at risk of gastrointestinal or renal complications. Patients with low back pain or fibromyalgia may benefit from treatment with cyclobenzaprine.
Recent evidence showed similar effectiveness at half of its manufacturer recommended dose 5 mg , but with fewer adverse effects. Higher doses of cyclobenzaprine or tizanidine would be appropriate to promote sedation in cases of more severe discomfort or perceived muscular spasm. Although there appears to be insufficient data on metaxalone and methocarbamol, these may be useful in patients who cannot tolerate the sedative properties of cyclobenzaprine or tizanidine.
Of note, methocarbamol costs substantially less than metaxalone. Carisoprodol is metabolized to meprobamate a class III controlled substance and has been shown to produce psychological and physical dependence.
Although all skeletal muscle relaxants should be used with caution in older patients, diazepam especially should be avoided in older patients or in patients with significant cognitive or hepatic impairment.
Already a member or subscriber? Log in. Interested in AAFP membership? Learn more. She received her doctor of pharmacy degree from Rutgers University College of Pharmacy in New Brunswick, NJ, and completed an inpatient family medicine pharmacy specialty residency at Deaconess Hospital and the St. Louis College of Pharmacy in St. Louis, Mo. She received her doctor of pharmacy degree from St. Reprints are not available from the authors. Carisoprodol carisoprodol tablet [package insert].
Philadelphia, Pa. Accessed January 14, But it may be detectable in urine from days after the consumption of Flexeril. Guay DR, Are there alternatives to the use of quinine to treat nocturnal leg cramps? Your email address will not be published. Save my name, email, and website in this browser for the next time I comment. Disclaimer: Painosoma. We are by no means advising our users to take any drugs talked about on our website.
In the case that the user does so, painosoma. Our main objective is to spread scientifically backed information to the users visiting our website and are not promoting a specific brand or product. Raunak Sushil Dandekar. July 19, October 26, What is Flexeril? What is Soma? Is Flexeril and Soma the same thing? What are the side effects of Flexeril and Soma? Drug interactions of Flexeril and Soma. Warnings and precautions of Flexeril and Soma.
It is the chemical that is responsible for your mood; it is a rare syndrome but a dangerous one as it can threaten your life too. If you are over 65 years old, then it will cause drowsiness, and remember not to consume alcohol while medicating with Flexeril.
It will cause you trouble urinating and get your eyes and mouth dry. It has been observed that people taking Flexeril will have liver problems.
For Soma- It can cause sedation. There are reports of accidents associated with the use of Soma. Overuse of Soma can lead to death. It may cause problems like depression, hypotension, seizures, and other disorders. But taking muscle relaxants, especially every day, isn't a good idea, according to our experts at Consumer Reports Best Buy Drugs. In fact, they recommend against taking Soma generic name carisoprodol at all because it poses a high risk of abuse and addiction, and isn't very effective.
Most people are better off skipping the other muscle relaxers, too, such as cyclobenzaprine Fexmid and generic , and metaxalone Skelaxin and generic , which can trigger potentially dangerous side effects, such as sedation and dizziness. Argoff, M. Soma carisoprodol in particular is a bad choice because of its abuse and addiction potential, Argoff adds.
It's been linked to a high number of emergency department visits and dozens of deaths and is the the only muscle relaxant classified as a controlled substance. Those strategies can sometimes help relieve headaches, neck pain, backaches and other conditions muscle relaxers are commonly prescribed to treat.
They ease pain as well as muscle relexants, but are safer, research shows. There are a few exceptions where muscle relaxers can be a preferred option, but only for a short period—no longer than three weeks and shorter if possible. For example, people with liver disease may not be able to take acetaminophen.
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